|
|
Research Interests |
- Structural and practical identifiability of non-linear systems
- MCMC-analysis of high-dimensional models
- Non-linear optimization for parameter estimation in systems biology
- ODE-based modelling
- Uncertainty analysis of non-linear systems
- Modelling of cell-signalling pathways
- Modelling of optogenetic gene expression
- Modelling of phase separation within cells
- Modelling of cancer cell growth and TGFß-signalling pathways
|
|
Publications |
Link to ORCID |
|
F-G. Wieland, A.L. Hauber, M. Rosenblatt, C. Tönsing, J. Timmer |
On structural and practical identifiability |
Current Opinion in Systems Biology (2021) 25 |
|
N. Schneider*, F-G. Wieland*, D. Kong, A.A.M. Fischer, M. Hörner, J. Timmer, H. Ye, W. Weber |
Liquid-Liquid Phase Separation of Light-Inducible Transcription Factors Increases Transcription Activation in Mammalian Cells and Mice |
PLoS Computational Biology (2021) 17(1): e1008646 |
* Shared first authorship |
|
L. Schmiester, Y. Schälte, F.T. Bergmann, T. Camba, E. Dudkin, J. Egert, F. Fröhlich, L. Fuhrmann, A.L. Hauber, S. Kemmer, P. Lakrisenko, C. Loos, S. Merkt, W. Müller, D. Pathirana, E. Raimúndez, L. Refisch, M. Rosenblatt, P.L. Stapor, P. Städter, D. Wang, F-G. Wieland, J.R. Banga, J. Timmer, A.F. Villaverde, S. Sahle, C. Kreutz, J. Hasenauer, D. Weindl |
PEtab - Interoperable specification of parameter estimation problems in systems biology |
PLoS Computational Biology (2021) 17(1): e1008646 |
|
|
R. Ochoa-Fernandez, N.B. Abel, F-G. Wieland, J. Schlegel, L.-A. Koch, J.B. Miller, R. Engesser, G. Giuriani, S.M. Brandl, J. Timmer, W. Weber, T. Ott, R. Simon, M.D. Zurbriggen |
PULSE: Optogenetic control of gene expression in plants in the presence of ambient white light |
Nature Methods (2020) 17 (717–725) |
|
Master thesis: Bayesian parameter estimation in systems biology: Markov chain Monte Carlo sampling of biochemical networks (link) |
|
Bachelor thesis: Implementation and assessment of optimization approaches for parameter estimation in systems biology (link) |
|
Teaching |
2021-SS
| Theoretische Physik III
|
2020-WS
| Experimentalphysik I
|
2020-SS
| Theoretische Physik I
|
2019-WS
| Theoretische Physik II
|
|
|