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Return to [[start|start page]] <grid> <col xs="12" sm="12" lg="4"> - [[ode_modelling#frameworks_toolboxes|Frameworks / Toolboxes]] \\ \\ - [[ode_modelling# generalization_benchmarking |Generalization/Benchmarking]] \\ \\ - [[ode_modelling#steady_states|Steady States]] \\ \\ - [[ode_modelling#input_estimation|Input Estimation ]] \\ \\ - [[ode_modelling#experimental_design|Experimental Design ]] \\ \\ - [[ode_modelling#integration_methods|Integration Methods]] \\ \\ - [[ode_modelling# optimization_improving_your_waterfall_plot|Optimization/Improving your waterfall plot]] \\ \\ - [[ode_modelling#parameter_estimation|Parameter Estimation]] \\ \\ - [[ode_modelling#identifiability_analysis_uncertainty_analysis|Identifiability Analysis / Uncertainty Analysis]] \\ \\ - [[ode_modelling#model_reduction|Model Reduction]] \\ \\ - [[ode_modelling#constraint_based_optimization|Constraint based optimization]] \\ \\ - [[ode_modelling#modelling_technique|Modelling Technique]] \\ \\ - [[ode_modelling#data_preprocessing_error_estimation|Data preprocessing / Error estimation]] \\ \\ - [[ode_modelling#model_prediction|Model Prediction]] \\ \\ - [[ode_modelling#ode_motifs|ODE Motifs]] \\ \\ - [[ode_modelling#single-cells|Single-Cells]] \\ \\ </col> <col xs="12" sm="12" lg="8"> <html> <svg version="1.1" viewBox="-0.5 -0.5 2712 1762" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"> <defs> <linearGradient id="mx-gradient-f5f5f5-1-b3b3b3-1-s-0" x1="0%" x2="0%" y1="0%" y2="100%"> <stop offset="0%" style="stop-color:#f5f5f5"/> <stop offset="100%" style="stop-color:#b3b3b3"/> </linearGradient> </defs> <g xlink:href="https://web.de/" target="_top"> <rect xlink:href="https://web.de/" target="_top" fill="#ffffff" height="1750" pointer-events="all" stroke="#000000" stroke-width="12" width="2700" x="6" y="6"/> <path d="M 636 901.6 L 656 901.6 L 662.17 901.42" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 670.41 901.17 L 659.58 907 L 662.17 901.42 L 659.25 896 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <ellipse cx="556" cy="901.5" fill="#ffff66" pointer-events="visiblePainted" rx="80" ry="80" stroke="#cccc00" stroke-width="5"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 158px; height: 1px; padding-top: 902px; margin-left: 477px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #000000; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Model <br style="font-size: 30px"/> construction</div> </div> </div> </foreignObject> <text fill="#000000" font-family="Times New Roman" font-size="30px" font-weight="bold" text-anchor="middle" x="556" y="911">Model...</text> </switch> </g> <path d="M 1176 901 L 1512.16 901" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1520.41 901 L 1509.41 906.5 L 1512.16 901 L 1509.41 895.5 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1086 1001 L 1086 1056 L 556 1056 L 556 995.34" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 556 987.09 L 561.5 998.09 L 556 995.34 L 550.5 998.09 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <rect fill="#dae8fc" height="200" pointer-events="visiblePainted" rx="27" ry="27" stroke="#6c8ebf" stroke-width="5" width="180" x="996" y="801"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 178px; height: 1px; padding-top: 901px; margin-left: 997px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #000000; line-height: 1.2; pointer-events: all; white-space: normal; word-wrap: normal; "> <b style="font-size: 30px">Structural identifiability analysis</b></div> </div> </div> </foreignObject> <text fill="#000000" font-family="Times New Roman" font-size="30px" text-anchor="middle" x="1086" y="910">Structural i...</text> </switch> </g> <path d="M 1706 901 L 1882.6 901 L 2045.16 901.46" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 2053.41 901.48 L 2042.39 906.95 L 2045.16 901.46 L 2042.43 895.95 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1706 901 L 1806 901 L 1806 1372.16" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1806 1380.41 L 1800.5 1369.41 L 1806 1372.16 L 1811.5 1369.41 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1616 1001 L 1616 1191 L 1519.84 1191" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1511.59 1191 L 1522.59 1185.5 L 1519.84 1191 L 1522.59 1196.5 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <rect fill="#f8cecc" height="200" pointer-events="visiblePainted" rx="27" ry="27" stroke="#b85450" stroke-width="5" width="180" x="1526" y="801"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 178px; height: 1px; padding-top: 901px; margin-left: 1527px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #000000; line-height: 1.2; pointer-events: all; white-space: normal; word-wrap: normal; "> <b style="font-size: 30px">Practical identifiability analysis</b></div> </div> </div> </foreignObject> <text fill="#000000" font-family="Times New Roman" font-size="30px" text-anchor="middle" x="1616" y="910">Practical id...</text> </switch> </g> <path d="M 906 901 L 982.16 901" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 990.41 901 L 979.41 906.5 L 982.16 901 L 979.41 895.5 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <rect fill="#f5f5f5" height="170" pointer-events="visiblePainted" rx="25.5" ry="25.5" stroke="#666666" stroke-width="5" width="230" x="676" y="816"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 228px; height: 1px; padding-top: 901px; margin-left: 677px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #333333; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Model fitting and uncertainty analysis</div> </div> </div> </foreignObject> <text fill="#333333" font-family="Times New Roman" font-size="30px" font-weight="bold" text-anchor="middle" x="791" y="910">Model fitting an...</text> </switch> </g> <ellipse cx="2586" cy="901.5" fill="#ffff00" pointer-events="visiblePainted" rx="80" ry="80" stroke="#d6b656" stroke-width="5"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 158px; height: 1px; padding-top: 902px; margin-left: 2507px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #000000; line-height: 1.2; pointer-events: all; white-space: normal; word-wrap: normal; ">Final <br style="font-size: 30px"/> validated <br style="font-size: 30px"/> model</div> </div> </div> </foreignObject> <text fill="#000000" font-family="Times New Roman" font-size="30px" text-anchor="middle" x="2586" y="911">Final...</text> </switch> </g> <path d="M 1426 1106 L 1426 901 L 1512.16 901" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1520.41 901 L 1509.41 906.5 L 1512.16 901 L 1509.41 895.5 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1346 1191 L 556 1191 L 556 995.34" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 556 987.09 L 561.5 998.09 L 556 995.34 L 550.5 998.09 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 2219 901.5 L 2252.6 901.6 L 2272.16 901.25" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 2280.41 901.1 L 2269.51 906.8 L 2272.16 901.25 L 2269.31 895.8 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 2366 986 L 2366 1706 L 556 1706 L 556 995.34" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 556 987.09 L 561.5 998.09 L 556 995.34 L 550.5 998.09 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <rect fill="#f5f5f5" height="170" pointer-events="visiblePainted" rx="24" ry="24" stroke="#666666" stroke-width="5" width="160" x="2286" y="816"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 158px; height: 1px; padding-top: 901px; margin-left: 2287px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #333333; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Validation</div> </div> </div> </foreignObject> <text fill="#333333" font-family="Times New Roman" font-size="30px" font-weight="bold" text-anchor="middle" x="2366" y="910">Validation</text> </switch> </g> <path d="M 1686 1471 L 556 1471 L 556 995.34" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 556 987.09 L 561.5 998.09 L 556 995.34 L 550.5 998.09 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1686 1471 L 1216 1471 L 1216 919.84" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1216 911.59 L 1221.5 922.59 L 1216 919.84 L 1210.5 922.59 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <rect fill="#f8cecc" height="170" pointer-events="visiblePainted" rx="25.5" ry="25.5" stroke="#b85450" stroke-width="5" width="240" x="1686" y="1386"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 238px; height: 1px; padding-top: 1471px; margin-left: 1687px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #000000; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Experimental design</div> </div> </div> </foreignObject> <text fill="#000000" font-family="Times New Roman" font-size="30px" font-weight="bold" text-anchor="middle" x="1806" y="1480">Experimental des...</text> </switch> </g> <rect fill="#f8cecc" height="170" pointer-events="visiblePainted" rx="24" ry="24" stroke="#b85450" stroke-width="5" width="160" x="1346" y="1106"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 158px; height: 1px; padding-top: 1191px; margin-left: 1347px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #000000; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Model reduction</div> </div> </div> </foreignObject> <text fill="#000000" font-family="Times New Roman" font-size="30px" font-weight="bold" text-anchor="middle" x="1426" y="1200">Model reduc...</text> </switch> </g> <path d="M 2139 986.5 L 2139 1471 L 1939.84 1471" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 1931.59 1471 L 1942.59 1465.5 L 1939.84 1471 L 1942.59 1476.5 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <rect fill="#f5f5f5" height="170" pointer-events="visiblePainted" rx="24" ry="24" stroke="#666666" stroke-width="5" width="160" x="2059" y="816.5"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 158px; height: 1px; padding-top: 902px; margin-left: 2060px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 30px; font-family: Times New Roman; color: #333333; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Predictions</div> </div> </div> </foreignObject> <text fill="#333333" font-family="Times New Roman" font-size="30px" font-weight="bold" text-anchor="middle" x="2139" y="911">Predictions</text> </switch> </g> <path d="M 2446 901 L 2476 901 L 2492.16 901.27" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 2500.41 901.41 L 2489.32 906.72 L 2492.16 901.27 L 2489.5 895.72 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="691" y="701"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="691" y="701"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling#optimization_improving_your_waterfall_plot"> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; 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text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 246px; margin-left: 1507px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Helvetica; color: #FFFFFF; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Frameworks / Toolboxes</div> </div> </div> </foreignObject> <text fill="#FFFFFF" font-family="Helvetica" font-size="24px" font-weight="bold" text-anchor="middle" x="1606" y="253">Frameworks / Tool...</text> </switch> </g> </a> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="216" y="921.5"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="216" y="921.5"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling #input_estimation" > <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 972px; margin-left: 217px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Helvetica; color: #FFFFFF; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Input Estimation</div> </div> </div> </foreignObject> </a> <text fill="#FFFFFF" font-family="Helvetica" font-size="24px" font-weight="bold" text-anchor="middle" x="316" y="979">Input Estimation</text> </switch> </g> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="1706" y="1576"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="1706" y="1576"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling#experimental_design"> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 1626px; margin-left: 1707px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Helvetica; color: #FFFFFF; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Experimental Design</div> </div> </div> </foreignObject> <text fill="#FFFFFF" font-family="Helvetica" font-size="24px" font-weight="bold" text-anchor="middle" x="1806" y="1633">Experimental Desi...</text> </switch> </g> </a> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="1246" y="701"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="1246" y="701"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling#identifiability_analysis_uncertainty_analysis"> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 751px; margin-left: 1247px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Helvetica; color: #FFFFFF; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Identifiability analysis</div> </div> </div> </foreignObject> <text fill="#FFFFFF" font-family="Helvetica" font-size="24px" font-weight="bold" text-anchor="middle" x="1346" y="758">Identifiability a...</text> </switch> </g> </a> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="1326" y="1296"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="1326" y="1296"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling#model_reduction"> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 1346px; margin-left: 1327px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Helvetica; color: #FFFFFF; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Model reduction</div> </div> </div> </foreignObject> <text fill="#FFFFFF" font-family="Helvetica" font-size="24px" font-weight="bold" text-anchor="middle" x="1426" y="1353">Model reduction</text> </switch> </g> </a> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="691" y="476"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="691" y="476"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling#modelling_technique"> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 526px; margin-left: 692px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Helvetica; color: #FFFFFF; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Modelling technique</div> </div> </div> </foreignObject> <text fill="#FFFFFF" font-family="Helvetica" font-size="24px" font-weight="bold" text-anchor="middle" x="791" y="533">Modelling techniq...</text> </switch> </g> </a> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="36" y="406"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="36" y="406"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling#data_preprocessing_error_estimation"> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 456px; margin-left: 37px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Helvetica; color: #FFFFFF; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Data preprocessing <br/> Error estimation</div> </div> </div> </foreignObject> </a> <text fill="#FFFFFF" font-family="Helvetica" font-size="24px" font-weight="bold" text-anchor="middle" x="136" y="463">Data preprocessin...</text> </switch> </g> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="2156" y="686"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="2156" y="686"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling#model_prediction"> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 736px; margin-left: 2157px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Helvetica; color: #FFFFFF; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Model prediction</div> </div> </div> </foreignObject> <text fill="#FFFFFF" font-family="Helvetica" font-size="24px" font-weight="bold" text-anchor="middle" x="2256" y="743">Model prediction</text> </switch> </g> </a> <rect fill="#000000" height="100" opacity="0.25" rx="15" ry="15" stroke="none" transform="translate(2,3)" width="200" x="216" y="1036"/> <rect fill="#10739e" height="100" pointer-events="visiblePainted" rx="15" ry="15" stroke="none" width="200" x="216" y="1036"/> <g transform="translate(-0.5 -0.5)"> <switch> <a href="doku.php?id=ode_modelling#ode_motifs"> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; 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text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 641px; margin-left: 267px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Times New Roman; color: #000000; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Prior knowledge from biologists</div> </div> </div> </foreignObject> <text fill="#000000" font-family="Times New Roman" font-size="24px" font-weight="bold" text-anchor="middle" x="366" y="648">Prior knowledge f...</text> </switch> </g> <path d="M 466 451 L 556 451 L 556 807.66" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 556 815.91 L 550.5 804.91 L 556 807.66 L 561.5 804.91 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 286 376 L 446 376 L 466 451 L 446 526 L 286 526 L 266 451 Z" fill="#ccff99" pointer-events="visiblePainted" stroke="#66cc00" stroke-miterlimit="10" stroke-width="5"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; text-align: left;" width="100%"> <div style="display: flex; align-items: unsafe center; justify-content: unsafe center; width: 198px; height: 1px; padding-top: 451px; margin-left: 267px;" xmlns="http://www.w3.org/1999/xhtml"> <div style="box-sizing: border-box; font-size: 0; text-align: center; "> <div style="display: inline-block; font-size: 24px; font-family: Times New Roman; color: #000000; line-height: 1.2; pointer-events: all; font-weight: bold; white-space: normal; word-wrap: normal; ">Measured data</div> </div> </div> </foreignObject> <text fill="#000000" font-family="Times New Roman" font-size="24px" font-weight="bold" text-anchor="middle" x="366" y="458">Measured data</text> </switch> </g> <path d="M 466 261 L 556 261 L 556 807.66" fill="none" pointer-events="stroke" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 556 815.91 L 550.5 804.91 L 556 807.66 L 561.5 804.91 Z" fill="#000000" pointer-events="visiblePainted" stroke="#000000" stroke-miterlimit="10" stroke-width="5"/> <path d="M 286 186 L 446 186 L 466 261 L 446 336 L 286 336 L 266 261 Z" fill="#ccff99" pointer-events="visiblePainted" stroke="#66cc00" stroke-miterlimit="10" stroke-width="5"/> <g transform="translate(-0.5 -0.5)"> <switch> <foreignObject height="100%" pointer-events="none" requiredFeatures="http://www.w3.org/TR/SVG11/feature#Extensibility" style="overflow: visible; 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